Niclosamide: indications, dosage regimen, contraindications
Русский

Niclosamide: regimen of use, mechanism of action, indications, contraindications

Release form

Tablets 0.25 g

Mechanism, spectrum of action

This medicine is an anthelmintic.

  • It disrupts oxidative phosphorylation,
  • acts on two layers of cestode tegument,
  • causes paralysis of neuromuscular tissue,
  • reduces resistance to proteolytic enzymes,
  • reduces the viability of eggs.

Contraindications are hypersensitivity to the drug and pregnancy.

Application diagram

The drug is taken orally in the form of a fine powder. Before each dose, you need to take 2 g of baking soda.

Hymenolipedosis

Adults are recommended to take 2-3 g per day orally. The daily dose is taken in 4 doses every 2 hours (at 10, 12, 14 and 16 hours), food is taken at 8, 13 and 18 hours. Treatment is carried out for 4 days, after 4 days it is repeated.

  • Children under 2 years of age are prescribed 0.5 g per day,
  • children 3-6 years old – 1 g per day,
  • children 6-12 years old – 1.5 g per day,
  • children over 12 years old – 2 g per day

within 3 days. In case of relapse, it is necessary to repeat the course according to the same scheme.

Taeniasis , teniarynchosis , diphyllobothriasis

Adults are prescribed 2-3 g on an empty stomach, after 2 hours it is necessary to take a saline laxative, the dose is repeated after 1 month.

Children are recommended:

for helminthiasis caused by T. solium, 50 mg per kg of body weight once on an empty stomach, or 2-3 hours after a light breakfast or dinner;

for helminthiasis caused by T. saginata and D. latum, in the same daily doses, but half the dose is taken after breakfast, and the rest after 1 hour, followed by a saline laxative 2 hours after the last dose.

The scientific information provided is general and cannot be used to make a decision about the possibility of using a particular drug.

There are contraindications, consult your doctor.

data-matched-content-rows-num="4,2" data-matched-content-columns-num="1,2" data-matched-content-ui-type="image_stacked" data-ad-format=" autorelaxed">
Niclosamide: regimen of use, mechanism of action, indications, contraindications Link to main publication
The scientific information provided is general and cannot be used to make treatment decisions. There are contraindications, consult your doctor.